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SCHEMBL19823068

SCHEMBL19823068

Cc1cc(C)c(S(=O)(=O)N2CCN(C3CCN(CCc4cc(C)c(S(=O)(=O)N5CCC(N6CCCCCC6)CC5)c(C)c4)CC3)CC2)c(C)c1

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ EBP Q15125 5/20 0.74
▸ DHCR7 Q9UBM7 5/20 0.74
▸ ALDH1A1 P00352 2/20 0.52
▸ KDM4E B2RXH2 1/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ EPHX2 P34913 7/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ LMNA P02545 1/20 0.43
▸ VEGFA P15692 1/20 0.43
▸ EGLN1 Q9GZT9 1/20 0.43
▸ L3MBTL3 Q96JM7 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17007435 0.86 EBP (1.00) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL17007504 0.86 EBP (1.00) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL17007461 0.85 EBP (0.97) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL17007491 0.80 EBP (0.72) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL17007476 0.80 EBP (0.77) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL21324573 0.76 EBP (0.60) EBPDHCR7ALDH1A1NPSR1EPHX2
SCHEMBL17007433 0.75 DHCR7 (1.00) EBPDHCR7ALDH1A1KDM4ENPSR1
SCHEMBL7023845 0.74 KMT2A (0.67) EBPDHCR7ALDH1A1NPSR1EPHX2
SCHEMBL22080860 0.74 EBP (0.70) EBPDHCR7ALDH1A1KDM4EEPHX2
SCHEMBL22032981 0.74 EBP (0.78) EBPDHCR7ALDH1A1NPSR1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018022904-A2 COMPOUNDS AND METHODS OF PROMOTING MYELINATION CASE WESTERN RESERVE UNIVERSITY (US) 2018-02-01 — — WO disclosed