⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448994 | 0.79 | — | — | |
| SCHEMBL8744887 | 0.77 | — | — | |
| SCHEMBL22872700 | 0.76 | — | — | |
| SCHEMBL22306075 | 0.76 | — | — | |
| SCHEMBL24115125 | 0.72 | — | — | |
| SCHEMBL22182910 | 0.72 | — | — | |
| SCHEMBL10819298 | 0.72 | — | — | |
| SCHEMBL8744902 | 0.72 | — | — | |
| SCHEMBL766771 | 0.72 | — | — | |
| SCHEMBL10171755 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018020474-A1 | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | LUPIN LIMITED (IN) | 2018-02-01 | — | — | WO | disclosed |