Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239414 | 0.84 | NPC1 (0.50) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL7812585 | 0.84 | NPC1 (0.57) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL14405808 | 0.81 | NPC1 (0.58) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL8252614 | 0.80 | NPC1 (0.50) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL13547911 | 0.80 | NPC1 (0.53) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL8655251 | 0.79 | NPC1 (0.58) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL21588483 | 0.78 | SMN1; SMN2 (0.53) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL24490258 | 0.78 | NPC1 (0.48) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL28218777 | 0.78 | SMN1; SMN2 (0.55) | NPC1SMN1; SMN2HPGDRAB9ATSHR | |
| SCHEMBL14741125 | 0.76 | NPC1 (0.58) | NPC1SMN1; SMN2HPGDRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2899185-B1 | Processes for preparing linezolid | UNIV INDIANA RES & TECH CORP (US) | 2018-01-31 | — | — | EP | disclosed |