SCHEMBL19829088

SCHEMBL19829088

CCCc1ccc(-c2cc(F)c(-c3cc(F)c(O)c(F)c3)c(F)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
RARB P10826 2/20 0.43
RARA P10276 1/20 0.43
RARG P13631 1/20 0.43
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CNR2 P34972 2/20 0.40
NISCH Q9Y2I1 1/20 0.40
CNR1 P21554 1/20 0.40
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALOX5 P09917 1/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39
GPR84 Q9NQS5 2/20 0.38
TP53 P04637 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16038459 0.93 MCL1 (0.49) MCL1RARBRARARARGESR1
SCHEMBL15965523 0.87 RARB (0.42) MCL1RARBRARARARGCNR2
SCHEMBL16488492 0.87 RARB (0.42) MCL1RARBRARARARGCNR2
SCHEMBL16572426 0.85 RARB (0.41) MCL1RARBRARARARGCNR2
SCHEMBL16258034 0.83 CYP17A1 (0.44) MCL1RARBRARARARGCNR2
SCHEMBL18416779 0.83 CYP17A1 (0.44) MCL1RARBRARARARGCNR2
SCHEMBL16584918 0.83 MCL1 (0.47) MCL1RARBRARARARGESR1
SCHEMBL13002230 0.83 RARB (0.40) MCL1RARBRARARARGCNR2
SCHEMBL13232851 0.81 NPC1 (0.40) MCL1RARBRARARARGCNR2
SCHEMBL13632415 0.81 NPC1 (0.44) MCL1RARBRARARARGCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10358602-B2 Liquid crystal compound having polyfluoro-2-butenoxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2019-07-23 US disclosed
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed