Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684310 | 0.95 | RXFP1 (0.66) | TSHRLMNANPSR1HTTRXFP1 | |
| Bamifylline SCHEMBL219043 | 0.92 | RXFP1 (0.60) | TSHRLMNANPSR1HTTRXFP1 | |
| Bamifylline SCHEMBL637064 | 0.91 | RXFP1 (0.58) | TSHRLMNANPSR1HTTRXFP1 | |
| Bamifylline SCHEMBL1648640 | 0.90 | RXFP1 (0.57) | TSHRLMNANPSR1HTTRXFP1 | |
| Bamifylline SCHEMBL27460692 | 0.86 | RXFP1 (0.53) | TSHRLMNANPSR1HTTRXFP1 | |
| Bamifylline SCHEMBL28086377 | 0.84 | TSHR (0.53) | TSHRLMNANPSR1HTTRXFP1 | |
| SCHEMBL684311 | 0.82 | MLNR (0.53) | TSHRLMNANPSR1HTTRXFP1 | |
| SCHEMBL683954 | 0.81 | RXFP1 (0.66) | TSHRLMNANPSR1HTTRXFP1 | |
| SCHEMBL8373802 | 0.81 | RXFP1 (0.72) | TSHRLMNANPSR1HTTRXFP1 | |
| SCHEMBL29376542 | 0.81 | RXFP1 (0.72) | TSHRLMNANPSR1HTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030453-A1 | METHOD FOR IMPROVING LEARNING | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030453-A1 | METHOD FOR IMPROVING LEARNING | NT5E, ADORA1, ENTPD5 | TSHR 2789/4885LMNA 1842/4885NPSR1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.