⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678318 | 0.86 | CA1 (0.33) | — | |
| SCHEMBL296484 | 0.83 | CA1 (0.38) | — | |
| SCHEMBL24899713 | 0.72 | — | — | |
| SCHEMBL19411425 | 0.72 | — | — | |
| SCHEMBL15695397 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL19411413 | 0.69 | — | — | |
| SCHEMBL362475 | 0.69 | — | — | |
| SCHEMBL23625041 | 0.67 | — | — | |
| SCHEMBL24931515 | 0.65 | — | — | |
| SCHEMBL25409479 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553077-A1 | SULFOXIMINE COMPOUND HAVING FGFR INHIBITORY EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Kinoteck Therapeutics Co., Ltd (CN) | 2025-05-14 | — | — | EP | disclosed |
| US-10307402-B2 | Azabenzimidazole derivatives as agonists of the AMP-activated protein kinase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-06-04 | — | — | US | disclosed |
| US-20180028500-A1 | New Azabenzimidazole Derivatives as Agonists of the AMP-Activated Protein Kinase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20180028500-A1 | New Azabenzimidazole Derivatives as Agonists of the AMP-Activated Protein Kinase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-01 | — | — | US | disclosed |