SCHEMBL19829657

SCHEMBL19829657

COCC1CCC(c2cc(F)c(C(F)(F)Oc3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GRM2 Q14416 1/20 0.32
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12625143 0.97 MEN1 (0.33) MEN1KMT2AL3MBTL1GRM2ALOX5AP
SCHEMBL19829744 0.94 MEN1 (0.31) MEN1KMT2AL3MBTL1
SCHEMBL12626180 0.92 CYP3A4 (0.31) MEN1KMT2AL3MBTL1
SCHEMBL19751187 0.91 GRM2 (0.32) GRM2ALOX5APFEN1
SCHEMBL12626181 0.90 CYP3A4 (0.33) MEN1KMT2AL3MBTL1
SCHEMBL19829717 0.90 GRM2 (0.32) GRM2
SCHEMBL12624317 0.89 GRM2 (0.33) GRM2ALOX5APFEN1
SCHEMBL19829655 0.89 GRM2 (0.33) MEN1KMT2AGRM2ALOX5APFEN1
SCHEMBL12624316 0.89 GRM2 (0.33) GRM2ALOX5APFEN1
SCHEMBL19829759 0.89 GRM2 (0.31) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030347-A1 LIQUID CRYSTAL COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed
US-20180030347-A1 LIQUID CRYSTAL COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed
EP-3275971-A1 LIQUID CRYSTAL COMPOUND HAVING DIFLUOROMETHYLENEOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-01-31 EP disclosed