SCHEMBL19830170

SCHEMBL19830170

OC(CCCC1CC2C=C[C@@H]1C2)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
LMNA P02545 1/20 0.32
HIF1A Q16665 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
PTGS2 P35354 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8402197 1.00 KDM4E (0.34) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL8402175 0.90 KDM4E (0.36) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL18713286 0.90 KDM4E (0.36) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL15779744 0.84 KDM4E (0.36) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL19380574 0.83 KDM4E (0.38) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL15800080 0.81 KDM4E (0.37) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL7539017 0.80 KDM4E (0.39) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL12198885 0.80 CES1 (0.32) KDM4EALDH1A1
SCHEMBL18714193 0.80 KDM4E (0.38) KDM4EALDH1A1CYP3A4CYP2D6MEN1
SCHEMBL3680032 0.80 KDM4E (0.38) KDM4EALDH1A1CYP3A4CYP2D6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10591818-B2 Nadic anhydride polymers and photosensitive compositions derived therefrom PROMERUS, LLC (US) 2020-03-17 US disclosed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US disclosed