Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HINT1 | P49773 | 4/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115914 | 1.00 | HPGD (0.62) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL412371 | 1.00 | HPGD (0.62) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL14143259 | 1.00 | HPGD (0.62) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL14440994 | 0.96 | HPGD (0.63) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL1738417 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL1738416 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL1738418 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL26208536 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL16317882 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A | |
| SCHEMBL12031280 | 0.93 | HPGD (0.64) | HPGDHINT1NT5EPNPGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018022221-A1 | PHOSPHORAMIDATE NUCLEOSIDE PRODRUG FOR TREATING VIRAL DISEASES AND CANCER, PROCESSES FOR THEIR PREPARATION AND THEIR USE | ASAVI, LLC (US) | 2018-02-01 | — | — | WO | disclosed |