Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | PI4KA | P42356 | 3/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.59 |
| ▸ | AHCY | P23526 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015788 | 0.87 | ADORA2A (0.69) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL1249908 | 0.87 | ADORA2A (0.69) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL608687 | 0.86 | CYP3A4 (0.68) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL3305032 | 0.86 | CYP3A4 (0.68) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL20502333 | 0.86 | ADORA2A (0.68) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL28883711 | 0.86 | ADORA2A (0.68) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL1249906 | 0.86 | ADORA2A (0.68) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| Water SCHEMBL28104578 | 0.85 | CYP3A4 (0.67) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| Water SCHEMBL28104561 | 0.85 | CYP3A4 (0.67) | ADORA2AADORA1CYP3A4PI4KAPI4K2B | |
| SCHEMBL15045890 | 0.84 | CYP3A4 (0.70) | ADORA2AADORA1CYP3A4PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018022221-A1 | PHOSPHORAMIDATE NUCLEOSIDE PRODRUG FOR TREATING VIRAL DISEASES AND CANCER, PROCESSES FOR THEIR PREPARATION AND THEIR USE | ASAVI, LLC (US) | 2018-02-01 | — | — | WO | disclosed |