⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805986 | 0.88 | — | — | |
| SCHEMBL18028937 | 0.88 | — | — | |
| SCHEMBL18028932 | 0.88 | — | — | |
| SCHEMBL18028993 | 0.84 | CYP3A4 (0.51) | — | |
| SCHEMBL18028958 | 0.84 | — | — | |
| SCHEMBL18028988 | 0.84 | — | — | |
| SCHEMBL18028995 | 0.84 | — | — | |
| SCHEMBL17274526 | 0.83 | — | — | |
| SCHEMBL9900182 | 0.82 | CYP2C8 (0.56) | — | |
| SCHEMBL17349647 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570108-B2 | Substituted benzofuran compounds for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180030019-A1 | SUBSTITUTED BENZOFURAN COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2018-02-01 | — | — | US | disclosed |