Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821147 | 1.00 | TAAR1 (0.56) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19821151 | 1.00 | TAAR1 (0.56) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19821145 | 0.88 | TAAR1 (0.56) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19821146 | 0.88 | TAAR1 (0.56) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19812820 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL20700301 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19812982 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL20703561 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7XBP1 | |
| SCHEMBL19812984 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7ALDH1A1 | |
| SCHEMBL19812818 | 0.84 | TAAR1 (0.55) | TAAR1HTR1ADRD2HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023072-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-01 | — | — | WO | disclosed |