Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640995 | 0.80 | TAAR1 (0.39) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL14478256 | 0.73 | SLC6A2 (0.52) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8092360 | 0.72 | SLC6A2 (0.47) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL14478267 | 0.71 | TAAR1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL3238216 | 0.71 | TAAR1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL2563200 | 0.71 | TAAR1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL29687549 | 0.71 | TAAR1 (0.50) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL19831977 | 0.71 | TAAR1 (0.39) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL13692395 | 0.71 | SLC6A2 (0.45) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8977117 | 0.71 | SLC6A2 (0.45) | SLC6A2TAAR1MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023072-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2018-02-01 | — | — | WO | disclosed |