SCHEMBL1983229

SCHEMBL1983229

COC(=O)CCC(N)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.70
GSR P00390 2/20 0.58
GRM8 O00222 1/20 0.58
GRM6 O15303 1/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
CYP1A2 P05177 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
GRIA4 P48058 1/20 0.58
GRIN1 Q05586 1/20 0.58
GRIN2A Q12879 1/20 0.58
GRIK2 Q13002 1/20 0.58
GRIK3 Q13003 1/20 0.58
GRIN2B Q13224 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142983 1.00 SLC1A1 (0.70) SLC1A1GSRGRM8GRM6GRIN2D
SCHEMBL1666146 1.00 SLC1A1 (0.70) SLC1A1GSRGRM8GRM6GRIN2D
Hydrochloric Acid SCHEMBL19520881 0.98 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
SCHEMBL28377520 0.98 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
Ammonia Solution, Strong SCHEMBL27721206 0.98 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
SCHEMBL28160356 0.98 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
Hydrochloric Acid SCHEMBL10516366 0.98 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
SCHEMBL16343347 0.91 SLC1A1 (0.60) SLC1A1GSRGRM8GRM6GRIN2D
Leucine SCHEMBL8642033 0.89 SLC1A1 (0.68) SLC1A1GSRGRM8GRM6GRIN2D
Adipic Acid SCHEMBL6739298 0.89 SLC1A1 (0.58) SLC1A1GSRGRM8GRM6GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836017-A Organic long-acting fertilizer based on crosslinking, interpenetration and copolymerization and honeycomb fertilizer hiding process 山东土秀才生物科技有限公司 2023-10-03 CN claimed
EP-4467143-B1 METHOD FOR PREPARING 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE CELGENE CORP (US) 2026-03-11 EP disclosed
US-12510533-B2 Methods for treating multiple myeloma and the use of companion biomarkers for 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile CELGENE CORPORATION (US) 2025-12-30 US disclosed
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
EP-4467143-A2 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND Celgene Corporation (US) 2024-11-27 EP disclosed
US-20240366593-A1 ANTIPROLIFERATIVE COMPOUNDS AND BISPECIFIC ANTIBODY AGAINST BCMA AND CD3 FOR COMBINED USE SIGNAL PHARMACEUTICALS, LLC 2024-11-07 US disclosed
US-20240366738-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES INC (US) 2024-11-07 US disclosed
EP-3651766-B1 4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND CELGENE CORP (US) 2024-09-11 EP disclosed
CN-112399848-B Antiproliferative compounds and bispecific antibodies against BCMA and CD3 for combined use 细胞基因公司 2024-09-06 CN disclosed
US-12053466-B2 Antiproliferative compounds and bispecific antibody against BCMA and CD3 for combined use CELGENE CORPORATION (US) 2024-08-06 US disclosed
CN-1232395-A Pharmaceutical compounds containing polyamines substituted with electron affinity groups UNIV FLORIDA STATE (US) 1999-10-20 CN disclosed
WO-1999020785-A1 PRODUCTION OF GLUTAMATE USING WILD TYPE BACILLUS METHANOLICUS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-04-29 WO disclosed
EP-0784629-B1 PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES DARWIN DISCOVERY LTD (GB) 1999-04-28 EP disclosed
WO-1998014190-A9 PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS 1998-07-30 WO disclosed
WO-1998014190-A1 PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS FLORIDA STATE UNIVERSITY (US) 1998-04-09 WO disclosed
WO-1994028012-A1 HYDROXAMATE INHIBITORS OF ENDOTHELIN CONVERTING ENZYME WARNER-LAMBERT COMPANY (US) 1994-12-08 WO disclosed
US-5338760-A Urea derivatives, their preparation and medicinal products containing them RHONE-POULENC RORER S.A. (FR) 1994-08-16 US disclosed
EP-0443559-A2 HIV protease inhibiting agents BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-08-28 EP disclosed
EP-0443573-A2 HIV protease inhibitors containing derived amino acids BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1991-08-28 EP disclosed
US-4425280-A POLYMER STABILIZERS FERRO CORPORATION (US) 1984-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366593-A1 ANTIPROLIFERATIVE COMPOUNDS AND BISPECIFIC ANTIBODY AGAINST BCMA AND CD3 FOR COMBINED USE CD4, CD2, CD22 SLC1A1 1037/4885GSR 4841/4885GRM8 1539/4885
US-12510533-B2 Methods for treating multiple myeloma and the use of companion biomarkers for 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile IKZF1, IKZF3, IKZF2 SLC1A1 1299/4885GSR 4882/4885GRM8 4710/4885
US-12053466-B2 Antiproliferative compounds and bispecific antibody against BCMA and CD3 for combined use CD4, CD2, CD22 SLC1A1 1037/4885GSR 4841/4885GRM8 1539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.