SCHEMBL19833

SCHEMBL19833

COC(=O)c1cc[c]cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA12 O43570 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
MAPT P10636 6/20 0.52
ALDH1A1 P00352 2/20 0.52
LOXL2 Q9Y4K0 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
XDH P47989 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28104110 1.00 TSHR (0.60) TSHRCA1CA2CA12CA7
SCHEMBL694482 0.87 CA1 (0.56) TSHRCA1CA2CA12CA7
Water SCHEMBL22720573 0.85 CA1 (0.76) TSHRCA1CA2CA12CA7
SCHEMBL5505996 0.84 CA1 (0.60) TSHRCA1CA2CA12CA7
Octanedioate SCHEMBL27905502 0.84 POLB (0.51) TSHRCA1CA2CA12CA7
SCHEMBL28993944 0.82 CA1 (0.80) TSHRCA1CA2CA12CA7
SCHEMBL23600 0.82 CA1 (0.80) TSHRCA1CA2CA12CA7
SCHEMBL28704033 0.79 CA1 (0.76) TSHRCA1CA2CA12CA7
Ammonia Solution, Strong SCHEMBL28873355 0.79 CA1 (0.76) TSHRCA1CA2CA12CA7
SCHEMBL28531063 0.79 CA1 (0.76) TSHRCA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8841 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324729-A Synthesis method of 3-alkenyl benzofuran compound 青岛科技大学 2024-07-12 CN claimed
CN-118324812-A Nitrogen-phosphine compound, and preparation method and application thereof 河南大学 2024-07-12 CN claimed
CN-118324806-A Diaryl alkyl phosphine and preparation method and application thereof 河南大学 2024-07-12 CN claimed
CN-118307569-A 2-Aryl-4-boron heterocyclic compound, and stereoselective preparation method and application thereof 武汉大学 2024-07-09 CN claimed
CN-118207552-A Method for preparing 4-organic selenium isoxazole compound by electrochemical oxidation method 浙江工业大学 2024-06-18 CN claimed
CN-116496506-B Preparation method and application of mesoporous crystalline material with super-large primary three-dimensional cage structure 武汉大学 2024-05-03 CN claimed
CN-117756767-A Preparation method of gamma, gamma-difluoroallylaldehyde compound and derivative thereof 南京林业大学 2024-03-26 CN claimed
CN-114805156-B Method for preparing asymmetric aryl seleno ether compound by copper catalysis under room temperature and water phase conditions 浙江工业大学 2024-03-26 CN claimed
EP-3189049-B1 PHTHALAZINE DERIVATIVES OF FORMULA (I) AS PCAF AND GCN5 INHIBITORS FOR USE IN THE TREATMENT OF CANCER GENENTECH INC (US) 2024-03-20 EP claimed
CN-111868038-B Compound, photoresist composition comprising the same, photoresist pattern comprising the same, and method for manufacturing the photoresist pattern 株式会社LG化学 2024-03-12 CN claimed
US-4217448-A MONIC ACID DERIVATIVES BEECHAM GROUP LIMITED (GB) 1980-08-12 US claimed
US-4208520-A BACTERICIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1980-06-17 US claimed
EP-0012112-A1 Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY AG (CH) 1980-06-11 EP claimed
US-4148995-A FROM AN AZETIDINONE AND A FURANONE, MULTISTEP Petrzilka, Theodor (CH) 1979-04-10 US claimed
US-4147693-A βLactam antibiotics and process for their use BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US claimed
US-4085099-A AZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-04-18 US claimed
US-4049664-A ANTIALLERGENS, ANTIASTHMATICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-09-20 US claimed
US-4016195-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-05 US claimed
US-4009206-A CHOLESTEROL LOWERING AGENTS MURAI HIROMU 1977-02-22 US claimed
US-3965122-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-06-22 US claimed