SCHEMBL19835262

SCHEMBL19835262

CCCCCC/C=C\CCCCCCCCCCO[C@H]1CCNC1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.43
GBA1 P04062 1/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR2 Q9HBW0 1/20 0.40
LPAR3 Q9UBY5 1/20 0.40
TRPV1 Q8NER1 1/20 0.37
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19833700 1.00 CHRM1 (0.43) CHRM1GBA1LPAR1LPAR2LPAR3
SCHEMBL19684445 1.00 CHRM1 (0.43) CHRM1GBA1LPAR1LPAR2LPAR3
SCHEMBL19835246 1.00 CHRM1 (0.43) CHRM1GBA1LPAR1LPAR2LPAR3
SCHEMBL19834963 0.97 CHRM1 (0.43) CHRM1GBA1LPAR1LPAR2LPAR3
SCHEMBL12179814 0.96 CHRM1 (0.43) CHRM1
SCHEMBL19835251 0.96 CHRM1 (0.43) CHRM1
SCHEMBL19835253 0.96 CHRM1 (0.43) CHRM1
SCHEMBL19833602 0.91 GBA1 (0.46) CHRM1GBA1
SCHEMBL19834937 0.91 GBA1 (0.46) CHRM1GBA1
SCHEMBL14924890 0.89 CHRM1 (0.47) CHRM1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3275448-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES Kyowa Hakko Kirin Co., Ltd. (JP) 2018-01-31 EP disclosed