Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.52 |
| ▸ | TEC | P42680 | 10/20 | 0.52 |
| ▸ | TXK | P42681 | 10/20 | 0.52 |
| ▸ | BMX | P51813 | 10/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22887340 | 0.94 | BTK (0.51) | BTKTECTXKBMXPREP | |
| SCHEMBL19836454 | 0.94 | BTK (0.51) | BTKTECTXKBMXGPR119 | |
| SCHEMBL19836219 | 0.91 | BTK (0.48) | BTKTECTXKBMX | |
| SCHEMBL21729249 | 0.90 | BTK (0.49) | BTKTECTXKBMX | |
| SCHEMBL19836243 | 0.90 | BTK (0.46) | BTKTECTXKBMX | |
| SCHEMBL22887244 | 0.89 | BTK (0.52) | BTKTECTXKBMXGPR119 | |
| SCHEMBL19001730 | 0.88 | BTK (0.51) | BTKTECTXKBMX | |
| SCHEMBL20468662 | 0.88 | BTK (0.47) | BTKTECTXKBMX | |
| SCHEMBL22887260 | 0.88 | BTK (0.51) | BTKTECTXKBMX | |
| SCHEMBL19836460 | 0.88 | BTK (0.64) | BTKTECTXKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055843-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-02-20 | — | — | US | disclosed |
| US-20180030037-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055843-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LCK | BTK 1/4885TEC 7/4885TXK 263/4885 |
| US-20180030037-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LCK | BTK 1/4885TEC 7/4885TXK 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.