SCHEMBL19838232

SCHEMBL19838232

Cc1cc(C)c(N2C(=O)c3ccccc3C2=O)c(C)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
DPP4 P27487 3/20 0.53
ANPEP P15144 2/20 0.53
TSHR P16473 2/20 0.47
GRM5 P41594 1/20 0.45
POLB P06746 1/20 0.45
MAPK1 P28482 2/20 0.45
NR1H2 P55055 1/20 0.45
NR1H3 Q13133 1/20 0.45
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
F2 P00734 1/20 0.44
GAA P10253 1/20 0.44
TLR9 Q9NR96 1/20 0.44
HSD17B10 Q99714 1/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14582061 0.84 DPP4 (0.49) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL10491139 0.83 DPP4 (0.68) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL17028351 0.81 KMT2A (0.47) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL19365931 0.80 DPP4 (0.55) DPP4ANPEP
SCHEMBL19834886 0.80 DPP4 (0.55) DPP4ANPEP
SCHEMBL12204686 0.79 KMT2A (0.53) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL29544415 0.78 DPP4 (0.44) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL17028268 0.78 KMT2A (0.45) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL6268625 0.78 DPP4 (0.44) KMT2AMEN1DPP4ANPEPTSHR
SCHEMBL30792888 0.78 GRM5 (0.62) KMT2AMEN1TSHRGRM5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494113-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES cynora GmbH (DE) 2019-06-12 EP disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 EP disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 WO disclosed
WO-2018024724-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 WO disclosed