Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839904 | 1.00 | TLR2 (0.82) | TLR2 | |
| SCHEMBL19839602 | 0.96 | TLR2 (0.82) | TLR2 | |
| SCHEMBL19839605 | 0.96 | TLR2 (0.82) | TLR2 | |
| SCHEMBL19839871 | 0.96 | TLR2 (0.82) | TLR2 | |
| SCHEMBL19839830 | 0.91 | TLR2 (0.81) | TLR2 | |
| SCHEMBL19839682 | 0.91 | TLR2 (0.81) | TLR2 | |
| SCHEMBL19839561 | 0.90 | TLR2 (1.00) | TLR2 | |
| SCHEMBL19839558 | 0.90 | TLR2 (1.00) | TLR2 | |
| SCHEMBL19839738 | 0.90 | TLR2 (0.73) | TLR2 | |
| SCHEMBL19839740 | 0.90 | TLR2 (0.73) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3493814-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | Neuropore Therapies, Inc. (US) | 2019-06-12 | — | — | EP | claimed |
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | claimed |