SCHEMBL19840460

SCHEMBL19840460

OCC1OC(OC2CCC(O)CC2)C(O)C(O)C1O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.56
SYNJ2 O15056 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GJA1 P17302 1/20 0.45
GJB2 P29033 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.43
TYR P14679 1/20 0.43
MAPT P10636 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7688096 0.88 PTPN1 (0.57) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL20097839 0.88 PTPN1 (0.57) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL21012995 0.88 PTPN1 (0.57) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL11288598 0.88 PTPN1 (0.57) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL167126 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL20306175 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL1727956 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL18872330 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL16788268 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1
SCHEMBL27345634 0.86 PTPN1 (0.56) PTPN1SYNJ2MEN1KMT2AGJA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9883998-B2 Methods for lightening skin using arbutin compositions OMP, INC. (US) 2018-02-06 US disclosed