Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dibromoethane SCHEMBL4449264 | 0.96 | TSHR (0.41) | TSHRHSD17B10TDP1 | |
| 2-Bromoethanol SCHEMBL1472070 | 0.85 | — | — | |
| Ethylene Glycol SCHEMBL22007 | 0.80 | — | — | |
| Ethylene Glycol SCHEMBL8080969 | 0.80 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL9616343 | 0.80 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL6570599 | 0.80 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL15995529 | 0.80 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL8082558 | 0.80 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL27449247 | 0.76 | — | — | |
| Ethylene Glycol SCHEMBL27305226 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307590-A | Synthesis method of chiral alpha-alkenyl-beta-alkyl phosphate | 南京工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307589-A | Synthesis method of achiral alpha-alkenyl-beta-alkyl phosphate | 南京工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-116178312-B | Synthesis method of chiral cyclic ether | 武汉大学 | 2024-06-25 | — | — | CN | claimed |
| CN-116063209-B | Method for preparing benzylamine derivative by catalyzing amination of benzyl C-H bond through nickel under promotion of visible light | 上海沃凯生物技术有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117659080-A | Synthesis method of chiral alpha-aryl-beta-alkyl phosphate | 南京工业大学 | 2024-03-08 | — | — | CN | claimed |
| CN-115417859-B | Synthesis method of rizatriptan benzoate | 陕西师范大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117486740-A | Novel method for efficiently synthesizing chiral alpha-amino acid derivative by asymmetric reduction addition reaction of transition metal catalytic imine | 华东理工大学 | 2024-02-02 | — | — | CN | claimed |
| CN-117362271-A | Method for preparing nicotine | 湖北和诺生物工程股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-114907197-B | Preparation method of biaziridine-based photocrosslinking probe intermediate and derivative | 中国人民解放军海军军医大学 | 2024-01-02 | — | — | CN | claimed |
| CN-114874081-B | Preparation method of green efficient alpha-functionalized ketone | 中国人民解放军海军军医大学 | 2023-12-22 | — | — | CN | claimed |
| US-20220119331-A1 | Processes for the Preparation of Zuclomiphene Intermediates | THE BANK OF NOVA SCOTIA (CA) | 2022-04-21 | — | — | US | claimed |
| CN-114292300-A | Spiro-dihydrobenzothiolline phosphonite monoester compound, preparation and application thereof | 中国科学院上海有机化学研究所 | 2022-04-08 | — | — | CN | claimed |
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | APOTEX INC. (CA) | 2021-06-29 | — | — | US | claimed |
| CN-112939750-A | Method for transferring asymmetric functionalization by nickel-hydrogen catalysis olefin promoted by ligand relay strategy | 南京大学 | 2021-06-11 | — | — | CN | claimed |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | THE BANK OF NOVA SCOTIA (CA) | 2021-05-20 | — | — | US | claimed |
| CN-111254457-B | Electrochemical synthesis method of aromatic carboxylic acid and alkyl carboxylic acid | 四川大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112679290-A | Nickel-catalyzed asymmetric hydrogen alkynylation method for olefins and application of nickel-catalyzed asymmetric hydrogen alkynylation method in preparation of AMG837 | 南京大学 | 2021-04-20 | — | — | CN | claimed |
| CN-111254457-A | Electrochemical synthesis method of aromatic carboxylic acid and alkyl carboxylic acid | 四川大学 | 2020-06-09 | — | — | CN | claimed |
| CN-110878012-A | Synthetic method of E-type methyl styrene compound | 南京大学 | 2020-03-13 | — | — | CN | claimed |
| WO-2007140525-A1 | A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION | HOENIG MICHEL (AU) | 2007-12-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046638-B2 | Processes for the preparation of zuclomiphene and intermediates thereof | CYP3A43, UGT1A3, ZDHHC7 | TSHR 4282/4885HSD17B10 219/4885TDP1 4368/4885 |
| US-20210147337-A1 | Processes for the Preparation of Zuclomiphene and Intermediates Thereof | CYP3A43, UGT1A3, ZDHHC7 | TSHR 4282/4885HSD17B10 219/4885TDP1 4368/4885 |
| US-20220119331-A1 | Processes for the Preparation of Zuclomiphene Intermediates | CYP4F2, CYP4F12, CYP1A2 | TSHR 3878/4885HSD17B10 184/4885TDP1 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.