SCHEMBL1984465

SCHEMBL1984465

CCc1c(C(=O)Nc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)s1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 15/20 0.70
CNR2 P34972 12/20 0.70
PPARA Q07869 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984648 0.91 CNR2 (0.68) CNR1CNR2
SCHEMBL1985366 0.90 CNR1 (0.66) CNR1CNR2PPARA
SCHEMBL1984585 0.88 CNR1 (0.69) CNR1CNR2PPARA
SCHEMBL1986649 0.86 CNR1 (0.70) CNR1CNR2
SCHEMBL1986231 0.83 CNR1 (0.57) CNR1CNR2PPARA
SCHEMBL1984647 0.83 CNR1 (0.61) CNR1CNR2
SCHEMBL1983939 0.83 CNR1 (0.98) CNR1CNR2
SCHEMBL1984880 0.82 CNR1 (1.00) CNR1CNR2
SCHEMBL1984409 0.82 CNR1 (1.00) CNR1CNR2
SCHEMBL1983912 0.81 CNR1 (0.66) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602656-B1 PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS NEUROSCIENZE PHARMANESS S C A R L (IT) 2011-06-29 EP claimed