Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678107 | 0.88 | SLC22A12 (1.00) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851008 | 0.88 | SLC22A12 (1.00) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851105 | 0.85 | SLC22A12 (0.67) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851018 | 0.85 | SLC22A12 (0.67) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL23954470 | 0.85 | SLC22A12 (0.69) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851130 | 0.85 | SLC22A12 (0.80) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851156 | 0.83 | SLC22A12 (0.56) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851015 | 0.82 | SLC22A12 (0.66) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL19851111 | 0.82 | SLC22A12 (0.62) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL23954461 | 0.81 | SLC22A12 (0.64) | SLC22A12CYP2C9CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495362-B1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV SHANDONG (CN) | 2021-10-27 | — | — | EP | disclosed |
| EP-3495362-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shandong University (CN) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018023851-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2018-02-08 | — | — | WO | disclosed |