Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 17/20 | 0.61 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851705 | 0.91 | TLR2 (0.74) | TLR2CA1CA2 | |
| SCHEMBL19851496 | 0.91 | TLR2 (0.74) | TLR2CA1CA2 | |
| SCHEMBL19851520 | 0.91 | TLR2 (0.74) | TLR2CA1CA2 | |
| SCHEMBL19851494 | 0.90 | TLR2 (0.75) | TLR2CA1CA2 | |
| SCHEMBL19839551 | 0.90 | TLR2 (0.68) | TLR2MC4RMC1RMC3R | |
| SCHEMBL19839556 | 0.90 | TLR2 (0.68) | TLR2MC4RMC1RMC3R | |
| SCHEMBL19851495 | 0.88 | TLR2 (0.75) | TLR2CA1CA2 | |
| SCHEMBL19851482 | 0.87 | TLR2 (0.81) | TLR2MC4RMC1RMC3R | |
| SCHEMBL19851701 | 0.87 | TLR2 (0.81) | TLR2MC4RMC1RMC3R | |
| Hydrochloric Acid SCHEMBL19839683 | 0.86 | TLR2 (0.81) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |