Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 19/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839557 | 0.92 | TLR2 (0.58) | TLR2CTSSCTSK | |
| SCHEMBL19839559 | 0.92 | TLR2 (0.58) | TLR2CTSSCTSK | |
| SCHEMBL19851629 | 0.90 | TLR2 (0.55) | TLR2CTSSCTSK | |
| SCHEMBL19851698 | 0.87 | TLR2 (0.63) | TLR2CTSSCTSK | |
| SCHEMBL19851509 | 0.86 | TLR2 (0.56) | TLR2CTSSCTSK | |
| SCHEMBL19839694 | 0.86 | TLR2 (0.55) | TLR2CTSSCTSK | |
| SCHEMBL19839692 | 0.86 | TLR2 (0.55) | TLR2CTSSCTSK | |
| SCHEMBL19851749 | 0.85 | TLR2 (0.57) | TLR2 | |
| SCHEMBL19851500 | 0.83 | TLR2 (0.76) | TLR2 | |
| SCHEMBL19851522 | 0.82 | TLR2 (0.70) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |