SCHEMBL19851639

SCHEMBL19851639

CCOCCCNC(=O)[C@H](CCCCN)NCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 11/20 0.76
CPB1 P15086 1/20 0.49
CPB2 Q96IY4 1/20 0.49
TSHR P16473 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
CHRNA1 P02708 3/20 0.48
CHRNG P07510 3/20 0.48
CHRNB1 P11230 3/20 0.48
CHRND Q07001 3/20 0.48
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19839565 0.99 TLR2 (0.74) TLR2CPB1CPB2TSHRSIRT2
Hydrochloric Acid SCHEMBL19839568 0.99 TLR2 (0.74) TLR2CPB1CPB2TSHRSIRT2
SCHEMBL19839899 0.91 TLR2 (0.92) TLR2SIRT2SIRT1SIRT3CHRNA1
SCHEMBL19839897 0.91 TLR2 (0.92) TLR2SIRT2SIRT1SIRT3CHRNA1
SCHEMBL19839636 0.90 TLR2 (0.63) TLR2TSHRSIRT2SIRT1
SCHEMBL19839633 0.90 TLR2 (0.63) TLR2TSHRSIRT2SIRT1
Hydrochloric Acid SCHEMBL19839829 0.90 TLR2 (0.90) TLR2SIRT2SIRT1SIRT3CHRNA1
Hydrochloric Acid SCHEMBL19839828 0.90 TLR2 (0.90) TLR2SIRT2SIRT1SIRT3CHRNA1
SCHEMBL19851736 0.86 TLR2 (1.00) TLR2SIRT2SIRT1SIRT3CHRNA1
Hydrochloric Acid SCHEMBL19839583 0.85 TLR2 (0.98) TLR2SIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018026866-A1 LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION NEUROPORE THERAPIES, INC. (US) 2018-02-08 WO disclosed