Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 17/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839562 | 0.77 | TLR2 (0.57) | TLR2 | |
| SCHEMBL19839849 | 0.77 | TLR2 (0.57) | TLR2 | |
| SCHEMBL19851636 | 0.77 | TLR2 (0.53) | TLR2CA12CA1CA2CA3 | |
| SCHEMBL19851685 | 0.77 | TLR2 (0.49) | TLR2 | |
| SCHEMBL19851634 | 0.73 | TLR2 (0.48) | TLR2 | |
| SCHEMBL25837482 | 0.72 | PLA2G10 (0.47) | TLR2CA1CA2CA7CA9 | |
| SCHEMBL21538639 | 0.72 | MEN1 (0.43) | CA12CA1CA2CA3CA4 | |
| SCHEMBL19839780 | 0.72 | TLR2 (0.72) | TLR2CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL19839696 | 0.72 | TLR2 (0.88) | TLR2 | |
| SCHEMBL19839782 | 0.72 | TLR2 (0.72) | TLR2CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |