Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 20/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 16/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 13/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851505 | 0.95 | SIRT2 (0.67) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542807 | 0.91 | SIRT2 (0.65) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542949 | 0.91 | SIRT2 (0.65) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542810 | 0.91 | SIRT2 (0.65) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542951 | 0.91 | SIRT2 (0.65) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20543102 | 0.91 | SIRT2 (0.65) | SIRT2SIRT1SIRT3 | |
| SCHEMBL12148814 | 0.90 | MAPT (0.62) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20543025 | 0.89 | SIRT2 (0.62) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20543022 | 0.89 | SIRT2 (0.62) | SIRT2SIRT1SIRT3 | |
| SCHEMBL19851672 | 0.88 | SIRT2 (0.77) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |