Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 16/20 | 0.67 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839713 | 0.86 | TLR2 (0.70) | TLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL19159189 | 0.85 | TLR2 (0.75) | TLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL16153009 | 0.82 | TLR2 (0.74) | TLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL19851668 | 0.81 | TLR2 (0.61) | TLR2 | |
| SCHEMBL19839827 | 0.81 | TLR2 (0.73) | TLR2LPAR1LPAR3 | |
| SCHEMBL19839666 | 0.80 | TLR2 (0.68) | TLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL135007 | 0.80 | TLR2 (0.68) | TLR2LPAR1LPAR3LPAR2 | |
| SCHEMBL19851856 | 0.80 | TLR2 (0.61) | TLR2LPAR1LPAR3 | |
| SCHEMBL19851654 | 0.80 | TLR2 (0.61) | TLR2LPAR1LPAR3 | |
| SCHEMBL29262958 | 0.80 | TLR2 (0.76) | TLR2LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |