Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839622 | 0.85 | CYP3A4 (0.47) | HRH4HRH3 | |
| SCHEMBL18878684 | 0.79 | NLN (0.48) | NLN | |
| SCHEMBL16381379 | 0.79 | TLR2 (0.47) | NLN | |
| SCHEMBL7780217 | 0.78 | CYP3A4 (0.56) | HRH4HRH3 | |
| SCHEMBL7779386 | 0.78 | CYP3A4 (0.56) | HRH4HRH3 | |
| SCHEMBL7781926 | 0.78 | CYP3A4 (0.56) | HRH4HRH3 | |
| SCHEMBL18814488 | 0.77 | NLN (0.48) | NLN | |
| SCHEMBL18814487 | 0.77 | NLN (0.48) | NLN | |
| SCHEMBL18814486 | 0.77 | NLN (0.48) | NLN | |
| SCHEMBL18878647 | 0.77 | NLN (0.48) | NLN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |