Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 10/20 | 1.00 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.60 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNG | P07510 | 1/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851717 | 1.00 | TLR2 (1.00) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839644 | 0.99 | TLR2 (0.98) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839597 | 0.99 | TLR2 (0.98) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839642 | 0.99 | TLR2 (0.98) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839599 | 0.99 | TLR2 (0.98) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| SCHEMBL19839899 | 0.92 | TLR2 (0.92) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| SCHEMBL19839897 | 0.92 | TLR2 (0.92) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839828 | 0.91 | TLR2 (0.90) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| Hydrochloric Acid SCHEMBL19839829 | 0.91 | TLR2 (0.90) | TLR2SIRT1SIRT2SIRT3SIRT6 | |
| SCHEMBL19839567 | 0.91 | TLR2 (0.83) | TLR2SIRT1SIRT2SIRT3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |