Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834853 | 0.93 | NAMPT (0.47) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19834830 | 0.86 | NAMPT (0.51) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19851958 | 0.84 | NAMPT (0.47) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19834852 | 0.81 | NAMPT (0.58) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19834857 | 0.81 | NAMPT (0.73) | NAMPTCYP3A4CYP2C9DRD3DRD2 | |
| SCHEMBL21103998 | 0.80 | NAMPT (0.49) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19834837 | 0.79 | NAMPT (0.65) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19851943 | 0.78 | NAMPT (0.49) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19851922 | 0.78 | NAMPT (0.48) | NAMPTCYP3A4CYP2C9BCHEACHE | |
| SCHEMBL19834861 | 0.76 | NAMPT (0.48) | NAMPTCYP3A4CYP2C9BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018024907-A1 | PIPERIDINE DERIVATIVES FOR USE IN THE TREATMENT OF PANCREATIC CANCER | CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS CHUV (CH) | 2018-02-08 | — | — | WO | disclosed |