Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21183487 | 0.98 | HPGD (0.64) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL21142470 | 0.97 | HPGD (0.67) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL23946114 | 0.96 | HPGD (0.61) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL13779779 | 0.93 | HPGD (0.62) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL15107851 | 0.93 | HPGD (0.62) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL1096914 | 0.93 | HPGD (0.62) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL2820898 | 0.88 | HPGD (0.56) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL24438917 | 0.88 | HPGD (0.56) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL22439376 | 0.88 | HPGD (0.56) | HPGDEPHX1USP2SMN1; SMN2MEN1 | |
| SCHEMBL31045798 | 0.87 | HPGD (0.59) | HPGDEPHX1USP2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685729-B2 | C5a receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2023-06-27 | — | — | US | disclosed |
| US-20210122736-A1 | C5A RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD. (CH) | 2021-04-29 | — | — | US | disclosed |
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122736-A1 | C5A RECEPTOR MODULATORS | C5AR1, C3AR1, C5AR2 | HPGD 2541/4885EPHX1 1256/4885USP2 4032/4885 |
| US-11685729-B2 | C5a receptor modulators | C5AR1, C3AR1, C5AR2 | HPGD 2541/4885EPHX1 1256/4885USP2 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.