Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852942 | 0.85 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL19852940 | 0.85 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL19852944 | 0.84 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL24339036 | 0.80 | GRIN2B (0.50) | GRIN2BGRIN2C | |
| SCHEMBL19852813 | 0.79 | GRIN2B (0.58) | GRIN2BGRIN2C | |
| SCHEMBL19852952 | 0.79 | GRIN2B (0.55) | GRIN2BGRIN2C | |
| SCHEMBL24339072 | 0.78 | GRIN2B (0.57) | GRIN2BGRIN2C | |
| SCHEMBL24339067 | 0.78 | GRIN2B (0.84) | GRIN2BGRIN2C | |
| SCHEMBL24338655 | 0.78 | GRIN2B (0.53) | GRIN2BGRIN2C | |
| SCHEMBL24338580 | 0.76 | GRIN2B (0.55) | GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026779-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |