Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181304 | 0.94 | F10 (0.79) | F10KCNH2KLKB1 | |
| SCHEMBL13038378 | 0.93 | F10 (0.70) | F10KCNH2KLKB1 | |
| SCHEMBL12134211 | 0.92 | F10 (0.58) | F10KCNH2KLKB1NPC1RAB9A | |
| SCHEMBL10146405 | 0.89 | F10 (0.71) | F10KCNH2KLKB1 | |
| SCHEMBL12134203 | 0.89 | F10 (0.63) | F10NPC1RAB9A | |
| SCHEMBL5555159 | 0.89 | F10 (0.88) | F10KCNH2KLKB1 | |
| SCHEMBL5536214 | 0.89 | F10 (0.66) | F10KCNH2KLKB1 | |
| SCHEMBL10178340 | 0.87 | F10 (0.62) | F10KCNH2KLKB1NPC1RAB9A | |
| SCHEMBL13038377 | 0.87 | F10 (0.56) | F10KCNH2KLKB1NPC1RAB9A | |
| SCHEMBL10146292 | 0.86 | F10 (0.78) | F10KCNH2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | F10 13/4885KCNH2 1032/4885KLKB1 192/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | F10 13/4885KCNH2 1032/4885KLKB1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.