Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584855 | 0.94 | CHRM5 (0.58) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL12435217 | 0.94 | CHRM5 (0.58) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL13202734 | 0.92 | CHRM5 (0.61) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL10071718 | 0.92 | CHRM5 (0.61) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL22953689 | 0.92 | CHRM5 (0.61) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL8900782 | 0.92 | CHRM5 (0.56) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL18898074 | 0.92 | CHRM5 (0.68) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL10070997 | 0.92 | CHRM5 (0.61) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL12359083 | 0.84 | KCNH2 (0.45) | CHRM5ADRA2CACHEKCNH2HRH3 | |
| SCHEMBL25696091 | 0.84 | KCNH2 (0.45) | CHRM5ADRA2CACHEKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | CHRM5 4383/4885ADRA2C 3986/4885ACHE 599/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | CHRM5 4383/4885ADRA2C 3986/4885ACHE 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.