Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181231 | 0.93 | F10 (0.68) | F10KCNH2 | |
| SCHEMBL10180283 | 0.93 | F10 (0.68) | F10KCNH2 | |
| SCHEMBL10178718 | 0.92 | F10 (0.68) | F10KCNH2 | |
| SCHEMBL10146280 | 0.89 | F10 (0.86) | F10KCNH2 | |
| SCHEMBL10181434 | 0.88 | F10 (0.79) | F10KCNH2 | |
| SCHEMBL10179206 | 0.86 | F10 (0.78) | F10KCNH2KLKB1 | |
| SCHEMBL10146991 | 0.86 | F10 (0.78) | F10KCNH2KLKB1 | |
| SCHEMBL10146416 | 0.85 | F10 (0.74) | F10KCNH2 | |
| SCHEMBL10181319 | 0.85 | F10 (0.78) | F10KCNH2KLKB1 | |
| SCHEMBL10178808 | 0.83 | F10 (0.79) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | F10 13/4885KCNH2 1032/4885KLKB1 192/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | F10 13/4885KCNH2 1032/4885KLKB1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.