Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651994 | 1.00 | BCL2 (0.71) | BCL2 | |
| SCHEMBL30314156 | 0.97 | BCL2 (0.68) | BCL2 | |
| SCHEMBL19839505 | 0.94 | BCL2 (0.72) | BCL2 | |
| SCHEMBL22932497 | 0.94 | BCL2 (0.68) | BCL2 | |
| SCHEMBL26648404 | 0.93 | BCL2 (0.71) | BCL2 | |
| SCHEMBL2725390 | 0.92 | BCL2 (0.76) | BCL2 | |
| SCHEMBL19839480 | 0.91 | BCL2 (0.69) | BCL2 | |
| SCHEMBL23865989 | 0.91 | BCL2 (0.63) | BCL2 | |
| Hydrochloric Acid SCHEMBL1702258 | 0.91 | BCL2 (0.68) | BCL2 | |
| SCHEMBL1701766 | 0.90 | BCL2 (0.67) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129999-A1 | N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | The Regents Of The University Of Michigan (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-3672594-B1 | COMBINATION PRODUCT OF BCL-2 INHIBITOR AND MDM2 INHIBITOR AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3672595-B1 | COMBINATION PRODUCT OF BCL-2 INHIBITOR AND CHEMOTHERAPEUTIC AGENT AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2021-07-21 | — | — | EP | disclosed |
| EP-3494115-B1 | N-(PHENYLSULFONYL)BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-3569601-A2 | N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | The Regents of The University of Michigan (US) | 2019-11-20 | — | — | EP | disclosed |
| WO-2018027097-A1 | N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-08 | — | — | WO | disclosed |