SCHEMBL19854

SCHEMBL19854

Clc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 1.00
CYP1A2 P05177 6/20 1.00
ALDH1A1 P00352 6/20 0.53
HSD17B10 Q99714 4/20 0.53
TSHR P16473 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
NR4A2 P43354 2/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 2/20 0.48
CYP3A4 P08684 1/20 0.48
KEAP1 Q14145 1/20 0.48
HPRT1 P00492 1/20 0.48
PAX8 Q06710 1/20 0.44
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NR4A1 P22736 1/20 0.41
NR4A3 Q92570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351228 1.00 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL31310956 1.00 CYP2A6 (1.00) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Hydrochloric Acid SCHEMBL28744332 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Hydrochloric Acid SCHEMBL28557123 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Benzene SCHEMBL1286405 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Ammonia Solution, Strong SCHEMBL11442084 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL2959450 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Methane SCHEMBL3891848 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
Naphthalene SCHEMBL8141546 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL1315127 0.97 CYP2A6 (0.94) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17188 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122091474-A Preparation method of fiber mesh reinforced polyphenylene sulfide film 2026-05-26 CN claimed
EP-4745147-A1 METHOD FOR PRODUCING CYCLIC SILANE COMPOUND Kureha Corporation (JP) 2026-05-20 EP claimed
CN-120826097-B Visible light blind near infrared flexible organic photoelectric detector and preparation method and application thereof 南开大学 2026-05-19 CN claimed
CN-122060538-A Flash point improver, preparation method thereof, refrigerator oil and working fluid composition for refrigerator 珠海格力电器股份有限公司 2026-05-19 CN claimed
CN-122054805-A Semitransparent organic solar cell and preparation method thereof 浙江大学长三角智慧绿洲创新中心 2026-05-15 CN claimed
CN-122018206-A Electrochromic organic photovoltaic window system and application thereof in building enclosure 浙江大学长三角智慧绿洲创新中心 2026-05-12 CN claimed
EP-4731605-A1 METHOD FOR PREPARING ALIPHATIC DIISOCYANATES IN THE GAS PHASE Covestro Deutschland AG (DE) 2026-04-29 EP claimed
EP-4188585-B1 METHOD OF PRODUCING CARBON MOLECULAR SIEVE MEMBRANES DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-19 EP claimed
US-12472482-B2 Method of producing carbon molecular sieve membranes DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-18 US claimed
US-12421250-B2 Ternary photoactive layer composition and organic solar cell comprising same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-09-23 US claimed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
US-3999144-A Process for eliminating small-scale intensity fluctuations of laser beams QUANTEL S.A. (FR) 1976-12-21 US claimed
US-3996252-A Preparation of pure 1,8-dinitroanthraquinone BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed
US-3996251-A Preparation of pure 1,5-dinitroanthraquinone BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed
US-3988144-A SULFOLANE OR SULFOLENE TIN SUBSTITUTED THE PROCTER & GAMBLE COMPANY (US) 1976-10-26 US claimed
US-3983064-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US claimed
US-3976427-A Organic compounds SANDOZ LTD. (CH) 1976-08-24 US claimed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed
US-3970494-A Method for adhering one surface to another WESTERN ELECTRIC CO., INC. (US) 1976-07-20 US claimed
US-3966688-A Arylene sulfide copolymer production PHILLIPS PETROLEUM COMPANY (US) 1976-06-29 US claimed