SCHEMBL19854026

SCHEMBL19854026

C=CC(=O)N(C)CCc1ccc(-c2ccc(-c3ccc(C4CCC(CCCCC)CC4)cc3)c(CC)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SPHK1 Q9NYA1 11/20 0.38
▸ FFAR4 Q5NUL3 2/20 0.36
▸ CYP2C9 P11712 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ P2RY14 Q15391 1/20 0.33
▸ DGAT1 O75907 1/20 0.33
▸ SPHK2 Q9NRA0 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854625 0.96 SPHK1 (0.39) SPHK1FFAR4CYP2C9SPHK2
SCHEMBL19854037 0.96 SPHK1 (0.39) SPHK1FFAR4CYP2C9SPHK2
SCHEMBL19854084 0.94 SPHK1 (0.39) SPHK1FFAR4CYP2C9ALDH1A1LMNA
SCHEMBL19854021 0.91 CYP2C9 (0.35) SPHK1FFAR4CYP2C9ALDH1A1LMNA
SCHEMBL19854621 0.91 RARB (0.41) SPHK1FFAR4CYP2C9
SCHEMBL19854068 0.90 SPHK1 (0.39) SPHK1FFAR4CYP2C9ALDH1A1LMNA
SCHEMBL19854079 0.88 CYP2C9 (0.37) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL20370512 0.88 CYP2C9 (0.37) SPHK1FFAR4CYP2C9ALDH1A1LMNA
SCHEMBL19855108 0.88 SPHK1 (0.37) SPHK1FFAR4CYP2C9ALDH1A1LMNA
SCHEMBL19855107 0.88 SPHK1 (0.37) SPHK1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 SPHK1 906/4885FFAR4 2050/4885CYP2C9 3761/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 SPHK1 906/4885FFAR4 2050/4885CYP2C9 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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