SCHEMBL19854993

SCHEMBL19854993

C=CC(=O)N(C)CCCc1ccc(-c2ccc(C3CCC(CCCCC)CC3)cc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 1/20 0.40
▸ S1PR1 P21453 4/20 0.39
▸ S1PR5 Q9H228 4/20 0.39
▸ S1PR3 Q99500 3/20 0.39
▸ SPHK1 Q9NYA1 6/20 0.39
▸ CYP2C9 P11712 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ BTK Q06187 2/20 0.34
▸ FFAR4 Q5NUL3 1/20 0.33
▸ DGAT1 O75907 1/20 0.33
▸ SOAT1 P35610 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370505 0.97 RARB (0.39) RARBS1PR1S1PR5S1PR3SPHK1
SCHEMBL19854632 0.95 RARB (0.41) RARBS1PR1S1PR5S1PR3SPHK1
SCHEMBL19854989 0.92 S1PR1 (0.39) RARBS1PR1S1PR5S1PR3CYP2C9
SCHEMBL19854068 0.91 SPHK1 (0.39) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL19855004 0.90 RARB (0.41) RARBSPHK1CYP2C9BTKFFAR4
SCHEMBL19854023 0.90 RARB (0.39) RARBS1PR1S1PR5S1PR3SPHK1
SCHEMBL19853896 0.89 SPHK1 (0.46) SPHK1CYP2C9
SCHEMBL19855108 0.89 SPHK1 (0.37) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL19853900 0.88 SPHK1 (0.48) SPHK1CYP2C9
SCHEMBL19854037 0.88 SPHK1 (0.39) SPHK1CYP2C9FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 RARB 1437/4885S1PR1 444/4885S1PR5 1530/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 RARB 1437/4885S1PR1 444/4885S1PR5 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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