SCHEMBL19855286

SCHEMBL19855286

C=C(C)C(=O)NCCC1CCC(c2ccc(C3CCC(C4CCC(CCCCC)CC4)CC3)cc2F)CC1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRL1 P41146 18/20 0.41
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370554 1.00 OPRL1 (0.41) OPRL1ALDH1A1LMNAMAPT
SCHEMBL20370545 0.96 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19854013 0.96 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19855280 0.96 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19855361 0.93 OPRL1 (0.37) OPRL1ALDH1A1LMNAMAPT
SCHEMBL20370546 0.91 OPRL1 (0.36) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19855285 0.89 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19855313 0.89 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19855287 0.89 OPRL1 (0.39) OPRL1ALDH1A1LMNAMAPT
SCHEMBL19856031 0.87 CNR2 (0.35) ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 OPRL1 3416/4885ALDH1A1 3826/4885LMNA 1840/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 OPRL1 3416/4885ALDH1A1 3826/4885LMNA 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback