Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856625 | 0.92 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856775 | 0.88 | CHRM3 (0.59) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856713 | 0.85 | CHRM3 (0.62) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL1925878 | 0.84 | CHRM2 (0.74) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856762 | 0.84 | CHRM3 (0.60) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856546 | 0.83 | CHRM2 (0.64) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL20565727 | 0.83 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856764 | 0.83 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856825 | 0.81 | CHRM3 (0.83) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856591 | 0.81 | CHRM2 (0.61) | CHRM3CHRM2CHRM1CHRM5CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928880-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-14 | — | — | EP | claimed |