Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856631 | 0.90 | CHRM3 (0.56) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856658 | 0.85 | CHRM2 (0.85) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL5007122 | 0.84 | CHRM3 (0.77) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856624 | 0.84 | CHRM3 (0.80) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL5007125 | 0.84 | CHRM3 (0.77) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856619 | 0.84 | CHRM3 (0.55) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL19856714 | 0.82 | CHRM3 (0.74) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL1924243 | 0.81 | CHRM2 (1.00) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL1926099 | 0.81 | CHRM2 (1.00) | CHRM3CHRM2CHRM1CHRM5CHRM4 | |
| SCHEMBL2828617 | 0.81 | CHRM2 (1.00) | CHRM3CHRM2CHRM1CHRM5CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928880-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-14 | — | — | EP | claimed |