Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 14/20 | 0.64 |
| ▸ | RPS6KA2 | Q15349 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982732 | 1.00 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL14973203 | 1.00 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL14972956 | 1.00 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL14972957 | 1.00 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL14973201 | 1.00 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL12595294 | 0.83 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2 | |
| SCHEMBL1984202 | 0.83 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2 | |
| SCHEMBL14973049 | 0.83 | RPS6KA3 (0.60) | RPS6KA3RPS6KA2 | |
| SCHEMBL1982846 | 0.81 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL1981787 | 0.81 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509979-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | Boehringer Ingelheim International GmbH (DE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071725-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |