Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558761 | 0.90 | MYC (0.42) | AURKAAURKBMYCCDK2MPL | |
| SCHEMBL1006651 | 0.90 | MYC (0.42) | AURKAAURKBMYCCDK2MPL | |
| SCHEMBL8011562 | 0.88 | MYC (0.41) | AURKAAURKBMYCCDK2MPL | |
| SCHEMBL476699 | 0.88 | MYC (0.41) | AURKAAURKBMYCCDK2MPL | |
| SCHEMBL1001104 | 0.88 | TSHR (0.46) | MYCCDK2MPLSMN1; SMN2TSHR | |
| SCHEMBL8154480 | 0.88 | TSHR (0.46) | MYCCDK2MPLSMN1; SMN2TSHR | |
| SCHEMBL16075637 | 0.79 | MYC (0.43) | MYCCDK2SMN1; SMN2TSHRTTR | |
| SCHEMBL1823611 | 0.78 | TDP1 (0.42) | MYCCDK2SMN1; SMN2TSHRTTR | |
| SCHEMBL29467252 | 0.78 | TDP1 (0.42) | MYCCDK2SMN1; SMN2TSHRTTR | |
| SCHEMBL29714465 | 0.78 | TDP1 (0.42) | MYCCDK2SMN1; SMN2TSHRTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890231-B2 | Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |