Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399669 | 1.00 | PIK3C2B (0.30) | PIK3C2B | |
| SCHEMBL19860997 | 0.93 | — | — | |
| SCHEMBL19861014 | 0.93 | PIK3C2B (0.31) | PIK3C2B | |
| SCHEMBL16920130 | 0.93 | PIK3C2B (0.31) | PIK3C2B | |
| SCHEMBL16920175 | 0.93 | — | — | |
| SCHEMBL16920133 | 0.91 | PIK3C2B (0.31) | PIK3C2B | |
| SCHEMBL19861043 | 0.91 | — | — | |
| SCHEMBL16920157 | 0.91 | — | — | |
| SCHEMBL17399674 | 0.90 | — | — | |
| SCHEMBL17399684 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141906-A1 | INDOLE AND AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY | SHIONOGI & CO. , LTD. (JP) | 2018-05-24 | — | — | US | disclosed |
| US-9890119-B2 | Indole and azaindole derivative having AMPK-activating activity | SHIONOGI & CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141906-A1 | INDOLE AND AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY | PRKAA1, PRKAA2, PRKAG3 | PIK3C2B 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.