Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21073906 | 0.91 | TDP1 (0.55) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6901399 | 0.91 | TDP1 (0.55) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7640286 | 0.90 | TDP1 (0.41) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL11655565 | 0.89 | TDP1 (0.56) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7634946 | 0.88 | TDP1 (0.42) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7753275 | 0.86 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL4416096 | 0.85 | TDP1 (0.50) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6828633 | 0.85 | TDP1 (0.50) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL10017368 | 0.85 | TDP1 (0.50) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL2948251 | 0.85 | TDP1 (0.50) | TDP1KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |