Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18269265 | 0.83 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL18271598 | 0.83 | ADORA2A (0.56) | ADORA2AADORA3ADORA1 | |
| SCHEMBL7043856 | 0.83 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL6885552 | 0.78 | ADORA2A (0.83) | ADORA2A | |
| SCHEMBL6879417 | 0.72 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL1044059 | 0.71 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL18271425 | 0.71 | ADORA2A (0.59) | ADORA2AADORA3ADORA1 | |
| SCHEMBL6884462 | 0.71 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL7047131 | 0.69 | ADORA2A (0.69) | ADORA2A | |
| SCHEMBL6879387 | 0.69 | ADORA2A (0.73) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889082-B2 | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and BPH | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-13 | — | — | US | disclosed |