Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 9/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860656 | 1.00 | P2RY2 (0.41) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL15074422 | 0.85 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL17860915 | 0.84 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL17863929 | 0.84 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL19861727 | 0.84 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL17860666 | 0.84 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL19861807 | 0.84 | TDP1 (0.39) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL16373867 | 0.78 | SLC28A1 (0.41) | P2RY2P2RY4P2RY6TDP1P2RY14 | |
| SCHEMBL17860641 | 0.78 | P2RY2 (0.47) | P2RY2P2RY4P2RY6P2RY14SLC28A1 | |
| SCHEMBL19861729 | 0.78 | P2RY2 (0.47) | P2RY2P2RY4P2RY6P2RY14SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890188-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2018-02-13 | — | — | US | disclosed |